SAN MIGUEL DE ALLENDE rests at an elevation of 6,400 feet in Mexico’s central Sierra Madre highlands, its Gothic spires and baroque bell towers seeming to reach for the very heights of heaven. Steeped in more than 450 years of intrigue, art and romance, the crown jewel of colonial Mexico inspires a sense of wonder in every arrival—especially for wedding couples and their guests visiting Casa de Sierra Nevada, a member of the Orient-Express family of fine hotels.

The hotel’s nine historic mansions hold just 37 rooms and suites, many with fireplaces and all distinguished by exquisite fabrics, art and antiques. Brides and grooms select from three venues for their vows and festivities, including Salón de la Galería for intimate affairs and the portico-lined Jardin Principal for parties of up to 300 guests.

Guests can enjoy casual and fine dining at two prominent restaurants, relaxation at the pool and spa and sightseeing by foot, horseback, bike and hot-air balloon. Another favorite pastime: shopping for fine silver work, handcrafted leather products and local folk art along San Miguel de Allende’s cobblestone streets. In addition, the hotel’s esteemed cooking school offers programs ranging from one-hour classes to weeklong culinary events.